INDUCIBLE CRISPR ACTIVATION SCREEN FOR INTERFERON-STIMULATED GENES IDENTIFIES OAS1 AS A SARS-COV-2 RESTRICTION FACTOR.

Inducible CRISPR activation screen for interferon-stimulated genes identifies OAS1 as a SARS-CoV-2 restriction factor.

Interferons establish an antiviral state through the induction of hundreds of interferon-stimulated genes (ISGs).The mechanisms and viral specificities for most ISGs remain incompletely understood.To enable high-throughput interrogation of ISG antiviral functions in pooled genetic screens while mitigating potentially confounding effects of endogeno

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Perceived and Pursued Opportunities from Mass Deportation Threats: The Case of Haitian Migrant-Serving Nonprofit Organizations in the Dominican Republic

The threat of deportation is a common experience shared by migrants around the world.Migrant-serving nonprofit organizations must also contend with these threats.While there is considerable research on how nonprofits serve migrants, there is a lack of research that explores what mass deportation threats may mean for nonprofits actors and their work

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Direct Analysis in Real Time Mass Spectrometry for the Nondestructive Investigation of Conservation Treatments of Cultural Heritage

Today the long-term conservation of cultural heritage is a big challenge: often the artworks tommy todd ointment were subjected to unknown interventions, which eventually were found to be harmful.The noninvasive investigation of the conservation treatments to which they were subjected to is a crucial step in order to undertake the best conservation

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